Removes the skin from the left side of Isaac's head.
Tears fired from left eye have increased damage.
When used with Cain, tears will have a 50% chance to do increased damage.
- The Mulligan, Infestation, Guppy's Head, Guppy - The attack flies spawned by these items will deal increased damage if the last shot fired was a Chemical Peel shot.
- Brimstone, Technology - Every second laser fired will deal increased damage.
- Loki's Horns - Cross pattern will increase in damage if fired from left eye
- The muscle revealed from picking up this item is identical to the Dople, which can also be seen when the Razor Blade/Red Patch is activated.
- This item is likely a reference to the Batman villain Two-Face, who had the left side of his face hideously scarred with acid.