A baby with swollen lips, red eyes, and red skin.
Familiar that shoots a pair of blood tears diagonally every second while Isaac is firing.
- Picking up The Relic, Bomb Bag or Holy Water temporarily changes the Harlequin Baby into Brother Bobby. It reverts back once the room is left or until you get hit.
- This item is based on a real medical condition named Harlequin Ichthyosis that deforms infants, causing them to have scaly skin, a strangely shaped body, and sunken, red eyes and lips.